Donors with Melanoma History: The Risk to Ocular Tissue Recipients

Authors

Jennifer Y. Li, MD

Keywords

Melanoma; corneal transplantation; keratolimbal allograft; donor-recipient transmission

Abstract

Summary: A case of donor-to-recipient melanoma transmission from keratolimbal allograft tissue has recently been reported to the Eye Bank Association of America. In light of this potential life-threatening adverse event, this article reviews the literature on the topic of donor-to-recipient tumor transmission both in the context of ocular tissue transplantation and solid organ transplantation specifically as it pertains to donors with a history of malignant melanoma.