Alterations In the Measured Intraocular Pressure Following Corneal Collagen Cross Linking

Authors

Chase Liaboe MD, Stephen C. Kaufman MD, PhD, Joseph Bogaard MD, Corey J. Miller MD, Alessandro Meduri MD3

Abstract

Purpose: To evaluate the effect of corneal collagen crosslinking on measured intraocular pressure with indentation tonometry.

Setting: Department of ophthalmology and visual sciences, Medical College of Wisconsin, Milwaukee, Wisconsin; Department of ophthalmology, University of Messina, Italy.

Design: Retrospective chart review

Methods: A total of 60 keratoconic eyes who underwent corneal collagen cross linking (CXL) were included. Indentation (Tonopen) tonometry was used to evaluate intraocular pressure (IOP) preoperatively and at one, three, and six-month postoperative follow-up visits.

Results: The average preoperative IOP was 14.1 +/- 2.1. See Table 1. The average IOP at the 1-month, 3-month, and 6-month follow-up were 17.1 +/- 2.7, 15.8 +/- 2.3, and 16.8 +/- 1.8 respectively. Relative to the preoperative IOP, the IOP at the 1-month, 3-month, and 6-month follow-up were statistically higher.

Conclusion: A statistically significant increase was noted in measured IOP with a Tonopen after CXL for keratoconus, which is likely due to an increase in corneal rigidity after CXL.